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PubMed · 9149112

Rat tyrosine hydroxylase gene polymorphisms.

S Murru·L Pani·D Poddie·G Gessa·A Cao·M Pirastu
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Abstract

The rat tyrosine hydroxylase gene (TH) from a panel of outbred and inbred rat strains has been analysed by Southern blotting, restriction-endonuclease mapping and direct sequencing of PCR-amplified products for detecting DNA polymorphisms. Five polymorphic sites have been characterized. This information may be used in pharmacogenetic studies to determine the influence of the TH gene in animal models of affective disorders and addictive behaviours.

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AnimalsBase SequenceDNA PrimersIntronsMolecular Sequence DataPolymerase Chain ReactionPolymorphism, GeneticRatsRats, Inbred F344Rats, Inbred LewRats, Sprague-DawleyRats, WistarTyrosine 3-MonooxygenaseJournal ArticleResearch Support, Non-U.S. Gov't

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S Murru, L Pani, D Poddie, G Gessa, A Cao, M Pirastu. 1997. Rat tyrosine hydroxylase gene polymorphisms.. https://doi.org/10.1016/s0169-328x(97)00029-6

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