Bacterial surface display: trends and progress.

S Ståhl; M Uhlén

doi:10.1016/s0167-7799(97)01034-2

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Bacterial surface display: trends and progress.

S Ståhl·M Uhlén

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Abstract

Heterologous surface display on Gram-negative bacterial was first described a decade ago and is now an active research area. More recently, strategies for surface display on Gram-positive bacterial have also been devised and these carry some inherent advantages. Bacterial surface display has found a range of applications in the expression of various antigenic determinants, heterologous enzymes, single-chain antibodies, polyhistidyl tags and even entire peptide libraries. This article explains the basis of bacterial surface display and discusses current uses and possible future trends of this emerging technology.

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Bacteria Bacterial Vaccines Biotechnology Cell Membrane Enzymes Epitopes Gram-Negative Bacteria Gram-Positive Bacteria Immunoglobulin Fragments Recombinant Proteins Vaccines, Synthetic Journal Article Review

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S Ståhl, M Uhlén. 1997. Bacterial surface display: trends and progress.. https://doi.org/10.1016/s0167-7799(97)01034-2

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