[Modification of the DNA spatial structure when complexed with cisplatin].

S G Arutiunina; E Sh Mamasakhlisov; V F Morozov; E B Dalian; R E Khachikian; P O Vardevanian; P Orioli; B Bruni

PubMed · 9172682

[Modification of the DNA spatial structure when complexed with cisplatin].

S G Arutiunina·E Sh Mamasakhlisov·V F Morozov·E B Dalian·R E Khachikian·P O Vardevanian·P Orioli·B Bruni

Abstract

The experimental and theoretical analyses of the conformational transitions of DNA-cis-platinum complexes have been carried out. It is shown that at low concentrations of the ligand, the thermodynamic parameters of the helix-coil transition of the complexes are not the result of the local B-->A transition.

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Animals Cattle Cisplatin DNA DNA Adducts Models, Chemical Nucleic Acid Conformation Thermodynamics English Abstract Journal Article

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S G Arutiunina, E Sh Mamasakhlisov, V F Morozov, E B Dalian, R E Khachikian, P O Vardevanian, P Orioli, B Bruni. [Modification of the DNA spatial structure when complexed with cisplatin].. https://pubmed.ncbi.nlm.nih.gov/9172682/

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