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PubMed · 9175474

RNA editing: getting U into RNA.

M L Kable·S Heidmann·K D Stuart
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Abstract

RNA editing in kinetoplastid protozoa remodels the sequences of mitochondrial pre-mRNAs by the precise insertion and deletion of uridylate residues. These sequence changes are directed by small trans-acting RNAs, termed guide RNAs. The basic mechanistic pathway by which edited RNA is generated has recently been elucidated using in vitro systems capable of a full round of guide-RNA-directed editing.

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Base SequenceMolecular Sequence DataRNARNA EditingRNA, Guide, KinetoplastidaRNA, MessengerRecombinant Fusion ProteinsUridine MonophosphateJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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M L Kable, S Heidmann, K D Stuart. 1997. RNA editing: getting U into RNA.. https://doi.org/10.1016/s0968-0004(97)01041-4

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