Aging, immunity and neuroendocrine hormones.

R L Mosley

doi:10.1016/s0960-5428(97)00031-9

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Aging, immunity and neuroendocrine hormones.

R L Mosley

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Abstract

Recent evidence indicates that the neuroendocrine and immune systems are intimately integrated into one system that provides a complex homeostatic network. Disruption of one system by extrinsic factors such as stress or antigenic exposure usually has consequences on the other. With advancing age, a progressive disruption can be observed in both systems which may have profound implications with respect to age-associated pathologies, including autoimmunity. In this review evidence is summarized which supports the hypothesis that neuroendocrine factors influence the age-associated decline of the immune system.

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R L Mosley. 1996. Aging, immunity and neuroendocrine hormones.. https://doi.org/10.1016/s0960-5428(97)00031-9

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