Population statistics of protein structures: lessons from structural classifications.

S E Brenner; C Chothia; T J Hubbard

doi:10.1016/s0959-440x(97)80054-1

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Population statistics of protein structures: lessons from structural classifications.

S E Brenner·C Chothia·T J Hubbard

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Abstract

Structural classifications aid the interpretation of proteins by describing degrees of structural and evolutionary relatedness. They have also recently revealed strikingly skewed distributions at all levels; for example, a small number of folds are far more common than others, and just a few superfamilies are known to have diverged widely. The classifications also provide an indication of the total number of superfamilies in nature.

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S E Brenner, C Chothia, T J Hubbard. 1997. Population statistics of protein structures: lessons from structural classifications.. https://doi.org/10.1016/s0959-440x(97)80054-1

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