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PubMed · 9206267

[A double column double pH solid phase extraction and capillary GC/FID method for rapid simultaneous determination of acidic and basic drugs in human plasma].

F H Qiu·L Liu·Y Luo·Y Q Lu
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Abstract

A capillary gas chromatographic method for the rapid simultaneous identification and quantitation of acidic and basic drugs in human plasma is presented. A special double column solid phase extraction device was designed, in which two X-5 resin columns can extract drugs at different pH. The detection limits for acidic and basic drugs can reach 0.5 microgram.ml-1, while the time needed is only half of that when using commercial solid phase extraction cartridges.

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Anesthetics, LocalAntipsychotic AgentsChromatography, GasDiazepamHumansHypnotics and SedativesLidocainePhenothiazinesSecobarbitalEnglish AbstractJournal Article

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F H Qiu, L Liu, Y Luo, Y Q Lu. 1996. [A double column double pH solid phase extraction and capillary GC/FID method for rapid simultaneous determination of acidic and basic drugs in human plasma].. https://pubmed.ncbi.nlm.nih.gov/9206267/

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