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PubMed · 9232799

Dendritic signal integration.

J Eilers·A Konnerth
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Abstract

Recent studies have identified various forms of active dendritic signals that may contribute to neuronal integration. One of the most remarkable findings is the demonstration of highly localized Ca2+ transients that are limited to small dendritic segments and even to single dendritic spines. In addition, through use of the powerful two-photon excitation imaging technique, it has been possible to reveal the existence of dendritic Ca2+ signals under in vivo conditions. Finally, active backpropagation of action potentials into dendrites has been shown to boost dendritic Ca2+ signals supralinearly and, thus, to contribute to the induction of long-term potentiation.

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AnimalsCalciumDendritesNeuronal PlasticityPurkinje CellsSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov'tReview

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J Eilers, A Konnerth. 1997. Dendritic signal integration.. https://doi.org/10.1016/s0959-4388(97)80067-0

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