Ca2+-dependent regulation in neuronal gene expression.

H Bito; K Deisseroth; R W Tsien

doi:10.1016/s0959-4388(97)80072-4

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Ca2+-dependent regulation in neuronal gene expression.

H Bito·K Deisseroth·R W Tsien

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Abstract

Ca2+ is an important signal-transduction molecule that plays a role in many intracellular signaling pathways. Recent advances have indicated that in neurons, Ca2+-controlled signaling mechanisms cooperate in order to discriminate amongst incoming cellular inputs. Ca2+-dependent transcriptional events can thereby be made selectively responsive to bursts of synaptic activity of specific intensity or duration.

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Animals Calcium Gene Expression Hippocampus Neurons Signal Transduction Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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H Bito, K Deisseroth, R W Tsien. 1997. Ca2+-dependent regulation in neuronal gene expression.. https://doi.org/10.1016/s0959-4388(97)80072-4

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