Single-particle tracking: applications to membrane dynamics.

M J Saxton; K Jacobson

doi:10.1146/annurev.biophys.26.1.373

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Single-particle tracking: applications to membrane dynamics.

M J Saxton·K Jacobson

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Abstract

Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.

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Diffusion Humans Membrane Fluidity Membrane Lipids Membrane Proteins Microscopy, Video Journal Article Research Support, U.S. Gov't, P.H.S.Review

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M J Saxton, K Jacobson. 1997. Single-particle tracking: applications to membrane dynamics.. https://doi.org/10.1146/annurev.biophys.26.1.373

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