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PubMed · 9248960

Problems arising in antimicrobial therapy due to false susceptibility testing.

B A Cunha
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Abstract

In vitro antibiotic susceptibility testing provides clinicians with guidelines to assess microbial sensitivities to various antibiotics. However, susceptibility testing is a laboratory procedure which does not always reflect the in vivo situation. False susceptibility testing is often due to methodological/disk concentration problems. In vitro versus in vivo discrepancies may also occur because of problems with varying pH/antibiotic concentration at the infection site. Clinicians should use susceptibility testing as a guide, but must rely upon the patient's clinical response as the ultimate in vivo susceptibility test.

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HumansMicrobial Sensitivity TestsReproducibility of ResultsJournal ArticleReview

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B A Cunha. 1997. Problems arising in antimicrobial therapy due to false susceptibility testing.. https://pubmed.ncbi.nlm.nih.gov/9248960/

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