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Epithelial differentiation in Drosophila.

U Tepass
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Abstract

Our understanding of epithelial development in Drosophila has been greatly improved in recent years. Two key regulators of epithelial polarity, Crumbs and DE-cadherin, have been studied at the genetic and molecular levels and a number of additional genes are being analyzed that contribute to the differentiation of epithelial cell structure. Epithelial architecture has a profound influence on morphogenetic movements, patterning and cell-type determination. The combination of embryological and genetic/molecular tools in Drosophila will help us to elucidate the complex events that determine epithelial cell structure and how they relate to morphogenesis and other developmental processes.

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AnimalsBlastodermCadherinsCell CommunicationCell DifferentiationCell PolarityDigestive SystemDrosophilaEpithelial CellsEpitheliumMembrane ProteinsModels, BiologicalMorphogenesisJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

U Tepass. 1997. Epithelial differentiation in Drosophila.. https://doi.org/10.1002/bies.950190807

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