Articular cartilage chondrons: form, function and failure.

C A Poole

doi:10.1046/j.1469-7580.1997.19110001.x

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Articular cartilage chondrons: form, function and failure.

C A Poole

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Abstract

The chondrocyte and its pericellular microenvironment together represent the chondron, historically considered the primary structural, functional and metabolic unit of articular and other hyaline cartilages. This review summarises research over the last 10 years to establish the molecular anatomy, functional properties and metabolic contribution of the chondron in articular cartilage homeostasis, and its failure during the initiation and progression of degenerative osteoarthritis.

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Animals Cartilage, Articular Collagen Extracellular Matrix Humans Microscopy, Confocal Osteoarthritis Journal Article Research Support, Non-U.S. Gov't Review

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C A Poole. 1997. Articular cartilage chondrons: form, function and failure.. https://doi.org/10.1046/j.1469-7580.1997.19110001.x

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