How Salmonella became a pathogen.

E A Groisman; H Ochman

doi:10.1016/s0966-842x(97)01099-8

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How Salmonella became a pathogen.

E A Groisman·H Ochman

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Abstract

In many pathogens, virulence can be conferred by a single region of the genome. In contrast, the facultative intracellular lifestyle of Salmonella demands a large number of genes distributed around the chromosome. The evolution of Salmonella has been marked by the acquisition of several 'pathogenicity islands', each contributing to the unique virulence properties of this microorganism.

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Chromosome Mapping Gene Expression Regulation, Bacterial Genes, Bacterial Gram-Negative Bacteria Host-Parasite Interactions Phylogeny Salmonella Virulence Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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E A Groisman, H Ochman. 1997. How Salmonella became a pathogen.. https://doi.org/10.1016/s0966-842x(97)01099-8

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