Polypeptide growth factors: targeted delivery systems.

M E Nimni

doi:10.1016/s0142-9612(97)00050-1

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Polypeptide growth factors: targeted delivery systems.

M E Nimni

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Abstract

Growth factors are becoming extremely valuable tools in our attempts to understand the mechanisms that modulate cellular activities. Their targeting to appropriate cells and maintaining adequate pharmacological levels becomes essential, particularly in view of the different effects that these compounds have on various cells and the dose dependence of their response. Within this context, this review focuses primarily on the delivery of growth factors involved in the processes of wound healing and tissue repair.

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Animals Biocompatible Materials Biomedical Engineering Bone Morphogenetic Proteins Cicatrix, Hypertrophic Drug Delivery Systems Epidermal Growth Factor Fibroblast Growth Factor 2 Fracture Healing Growth Substances Humans Keloid Nerve Growth Factors Peptides Platelet-Derived Growth Factor Transforming Growth Factor beta Wound Healing Journal Article Review

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M E Nimni. 1997. Polypeptide growth factors: targeted delivery systems.. https://doi.org/10.1016/s0142-9612(97)00050-1

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