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Archaeal introns: splicing, intercellular mobility and evolution.

J Lykke-Andersen·C Aagaard·M Semionenkov·R A Garrett
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Abstract

Until recently, it appeared that archaeal introns were spliced by a process specific to the archaeal domain in which an endoribonuclease cuts a 'bulge-helix-bulge' motif that forms at exon-intron junctions. Recent results, however, have shown that the endoribonuclease involved in archaeal intron splicing is a homologue of two subunits of the enzyme complex that excises eukaryotic nuclear tRNA introns. Moreover, some archaeal introns encode homing enzymes that are also encoded by group I introns.

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ArchaeaEvolution, MolecularIntronsModels, MolecularNucleic Acid ConformationPhylogenyRNA SplicingRNA, BacterialRNA, TransferJournal ArticleResearch Support, Non-U.S. Gov'tReview

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J Lykke-Andersen, C Aagaard, M Semionenkov, R A Garrett. 1997. Archaeal introns: splicing, intercellular mobility and evolution.. https://doi.org/10.1016/s0968-0004(97)01113-4

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