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Interendothelial junctions: structure, signalling and functional roles.

M G Lampugnani·E Dejana
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Abstract

Endothelial cell-cell adhesive junctions are formed by transmembrane adhesive proteins linked to a complex cytoskeletal network. These structures are important not only for maintaining adhesion between endothelial cells and, as a consequence, for the control of vascular permeability, but also for intracellular signalling properties. The establishment of intercellular junctions might affect the endothelial functional phenotype by the downregulation or upregulation of endothelial-specific activities.

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AnimalsCell AdhesionEndotheliumHumansIntercellular JunctionsSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov'tReview

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M G Lampugnani, E Dejana. 1997. Interendothelial junctions: structure, signalling and functional roles.. https://doi.org/10.1016/s0955-0674(97)80121-4

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