Cracking the carbohydrate code for selectin recognition.

C R Bertozzi

doi:10.1016/1074-5521(95)90096-9

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Cracking the carbohydrate code for selectin recognition.

C R Bertozzi

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Abstract

Selectins are central in the inflammatory response; the discovery that they bind to carbohydrate ligands has galvanized carbohydrate chemists to search for inhibitors of the process. Recent progress in identifying and analyzing physiological selectin counter-receptors suggests new approaches to the design of ligands that bind to specific selectins.

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Animals Anti-Inflammatory Agents Carbohydrates Drug Design Humans Ligands P-Selectin Journal Article Research Support, Non-U.S. Gov't Review

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C R Bertozzi. 1995. Cracking the carbohydrate code for selectin recognition.. https://doi.org/10.1016/1074-5521(95)90096-9

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