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PubMed · 9399623

Delayed hypersensitivity reaction to vancomycin.

P E Marik·N Ferris
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Abstract

The use of vancomycin has increased dramatically in recent years with the emergence of methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci as important hospital pathogens. A patient receiving vancomycin 1.75 g intravenously as a single daily dose developed a syndrome characterized by high fever, erythema multiforme, eosinophilia, and presumed interstitial nephritis. This delayed hypersensitivity reaction resolved with discontinuation of the drug and treatment with methylprednisolone.

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Anti-Bacterial AgentsDrug HypersensitivityHumansHypersensitivity, DelayedMaleMiddle AgedPneumococcal InfectionsVancomycinCase ReportsJournal Article

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P E Marik, N Ferris. Delayed hypersensitivity reaction to vancomycin.. https://pubmed.ncbi.nlm.nih.gov/9399623/

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