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CCK biosynthesis and processing: recent progress and future challenges.

M C Beinfeld
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Abstract

The peptide cholecystokinin (CCK), like other peptides which pass through the regulated secretory pathway, undergoes a number of post-translational modifications during its biosynthesis including tyrosine sulfation, endoproteolytic cleavage, and trimming by carboxypeptidases. This minireview summarizes what is known about this process in endocrine cells and in the Cpe(fat)/Cpe(fat) mouse and points out what challenges remain for future research.

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M C Beinfeld. 1997. CCK biosynthesis and processing: recent progress and future challenges.. https://doi.org/10.1016/s0024-3205(97)00644-9

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