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Regulatory feedback pathways in the thymus.

R Mehr·A S Perelson·M Fridkis-Hareli·A Globerson
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Abstract

The idea that thymocytopoiesis may be subject to feedback regulation by mature lymphocytes is proposed on the basis of recent data from in vitro experimental models. Analysis of the data using mathematical models, presented here by Ramit Mehr and colleagues, suggests possible feedback control mechanisms in T-cell development.

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AnimalsCell DivisionFeedbackLymphocyte ActivationMajor Histocompatibility ComplexMiceModels, ImmunologicalT-LymphocytesThymus GlandJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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R Mehr, A S Perelson, M Fridkis-Hareli, A Globerson. 1997. Regulatory feedback pathways in the thymus.. https://doi.org/10.1016/s0167-5699(97)01150-x

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