Fitting new modalities into practice guidelines.

R L Theriault

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PubMed · 9430184

Fitting new modalities into practice guidelines.

R L Theriault

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Abstract

At M. D. Anderson, the use of the recently approved bisphosphonate pamidronate (Aredia) became a part of the standard of care pathway for the treatment of osteolytic metastases from breast cancer. How any agent achieves that status involves the long process of completing clinical trials and resolving many practical and ethical dilemmas. What criteria determine the standard of care and who decides what those criteria should be are two of the many questions that need to be answered before a treatment modality or specific agent becomes part of the standard of care. This article describes how pamidronate achieved that status at M. D. Anderson.

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Antineoplastic Agents Bone Neoplasms Bone and Bones Breast Neoplasms Data Interpretation, Statistical Diphosphonates Female Humans Osteolysis Pain Pamidronate Practice Guidelines as Topic Quality of Life Time Factors Clinical Trial Journal Article Multicenter Study Randomized Controlled Trial

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R L Theriault. 1997. Fitting new modalities into practice guidelines.. https://pubmed.ncbi.nlm.nih.gov/9430184/

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