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PubMed · 9440531

Staphylococcus aureus cap5O and cap5P genes functionally complement mutations affecting enterobacterial common-antigen biosynthesis in Escherichia coli.

K B Kiser·J C Lee
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Abstract

The Staphylococcus aureus cap5P and cap5O genes of the type 5 capsule biosynthetic locus restore enterobacterial common-antigen expression to Escherichia coli mutants defective in rffE and rffD gene expression, respectively. Cap5P and Cap5O likely function as UDP-GlcNAc 2-epimerase and UDP-ManNAc dehydrogenase enzymes, respectively, in the synthesis of the capsule precursor UDP-ManNAcA.

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Antigens, BacterialCarbohydrate SequenceEscherichia coliGenes, BacterialGenetic Complementation TestMolecular Sequence DataMutationStaphylococcus aureusJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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K B Kiser, J C Lee. 1998. Staphylococcus aureus cap5O and cap5P genes functionally complement mutations affecting enterobacterial common-antigen biosynthesis in Escherichia coli.. https://doi.org/10.1128/jb.180.2.403-406.1998

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