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PubMed · 9444866

Acute myelofibrosis.

S Das·B R Prabhakar
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Abstract

Acute myelofibrosis is a rare disorder. Five such cases have been diagnosed out of 3,149 Bone Marrow (B.M) Aspirations and Trephine Biopsies studied over a period of eight and a half years. Four out of five patients were males and the other female. Their age ranged from 14-71 years. Neither splenomegaly not red cell poikilocytosis (tear drop cells) were prominant features. B.M. trephine biopsy showed increase of atypical megakaryocytes/megakaryoblasts and marked fibrosis. There was rapid downhill clinical course of the disease in all cases.

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Acute DiseaseAdolescentAdultAgedBiopsy, NeedleBone MarrowBone Marrow CellsFemaleFibrosisFollow-Up StudiesHumansMaleMegakaryocytesPrimary MyelofibrosisJournal Article

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S Das, B R Prabhakar. 1997. Acute myelofibrosis.. https://pubmed.ncbi.nlm.nih.gov/9444866/

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