Pleuromutilins. Fermentation, structure and biosynthesis.

F Knauseder; E Brandl

doi:10.7164/antibiotics.29.125

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Pleuromutilins. Fermentation, structure and biosynthesis.

F Knauseder·E Brandl

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Abstract

Derivatives of pleuromutilin, formed during the fermentation of pleuromutilin, were isolated and their structure determined. 14-Acetyl-mutilin and mutilin as well as different unsaturated fatty acid esters of pleuromutilin were identified. The proportion of each derivative formed depends to a considerable degree on the conditions of the fermentation process. The possible biosynthetic pathways are shown.

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Agaricales Anti-Bacterial Agents Chemical Phenomena Chemistry Chromatography, Thin Layer Diterpenes Fermentation Polycyclic Compounds Time Factors Pleuromutilins Journal Article

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F Knauseder, E Brandl. 1976. Pleuromutilins. Fermentation, structure and biosynthesis.. https://doi.org/10.7164/antibiotics.29.125

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