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PubMed · 9456032

Affinity capillary electrophoresis.

G Rippel·H Corstjens·H A Billiet·J Frank
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Abstract

The application of affinity capillary electrophoresis (ACE) to the study of molecular interactions is reviewed. ACE appears to be a sensitive, versatile and convenient tool to obtain reliable data on binding constants and stoichiometries of interacting systems using the Hummel-Dreyer method and variants thereof. A powerful feature is the possibility to analyze simultaneously the affinity of a large number of compounds for the same ligand, making it a promising tool for the screening of large combinatorial libraries.

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Amino Acid SequenceDNAElectrophoresis, CapillaryHumansKineticsMolecular Sequence DataPeptidesProteinsJournal ArticleResearch Support, Non-U.S. Gov'tReview

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G Rippel, H Corstjens, H A Billiet, J Frank. 1997. Affinity capillary electrophoresis.. https://doi.org/10.1002/elps.1150181208

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