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PubMed · 9492981

Allergen gene transfer.

S K Huang·K Y Chua·K H Hsieh
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Abstract

DNA-based immunization induces a biased Th1 immune response, and offers a novel strategy for modulation of the Th2-associated response. Recent studies have provided evidence that antigen-induced allergic responses can be modulated in rodents immunized with plasmid DNAs encoding the sensitizing antigens. Further understanding of the regulatory mechanism involved and optimization of gene transfer/expression systems will assist greatly in proving the clinical utility of this process.

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Adjuvants, ImmunologicAllergensAnimalsGene Transfer TechniquesGenetic TherapyHumansHypersensitivityTh1 CellsTh2 CellsJournal ArticleReview

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BibTeXRIS

S K Huang, K Y Chua, K H Hsieh. 1997. Allergen gene transfer.. https://doi.org/10.1016/s0952-7915(97)80181-1

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