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A murine TSPY.

T Vogel·H Boettger-Tong·I Nanda·F Dechend·A I Agulnik·C E Bishop·M Schmid·J Schmidtke
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Abstract

Sequences homologous to human and bovine TSPY were isolated from M. musculus testicular cDNA, and a nearly full-length gene was polymerase chain reaction (PCR) amplified from mouse genomic DNA. This gene is apparently non-functional. Contrary to the situation encountered in species along the primate and artiodactyl lineages, in which TSPY is moderately repetitive, murine Tspy appears to be single copy. Murine Tspy is located on Yp, i.e. in the same syntenic group as in man. Sequence comparisons of murine, human and bovine TSPY exons suggest that TSPY became non-functional during rodent evolution.

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AnimalsChromosome MappingCloning, MolecularDNA-Binding ProteinsEvolution, MolecularExonsFemaleGene DosageMaleMiceMolecular Sequence DataNuclear ProteinsOpen Reading FramesPseudogenesRNA SplicingSequence Analysis, DNASequence Homology, Nucleic AcidSex-Determining Region Y ProteinTestisTranscription FactorsY ChromosomeJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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T Vogel, H Boettger-Tong, I Nanda, F Dechend, A I Agulnik, C E Bishop, M Schmid, J Schmidtke. 1998. A murine TSPY.. https://doi.org/10.1023/a%3A1009214307764

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