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PubMed · 9519291

Helicases: a unifying structural theme?

L E Bird·H S Subramanya·D B Wigley
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Abstract

The recent structure determinations of PcrA DNA helicase, NS3 RNA helicase, and Rep DNA helicase have revealed similarities between their folds. When these data are examined with sequence and biochemical analyses, as well as microscopy studies of hexameric helicases, a picture of a unifying structure and mechanism for all helicases is beginning to emerge.

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DNADNA HelicasesModels, MolecularProtein FoldingStructure-Activity RelationshipJournal ArticleReview

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L E Bird, H S Subramanya, D B Wigley. 1998. Helicases: a unifying structural theme?. https://doi.org/10.1016/s0959-440x(98)80004-3

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