A mitogenic and hormonal signalling network regulate mammalian cell division commitment time.

L Jimenez de Asua; M Goin; M Ortiz; M B Gomez de Alzaga

doi:10.1007/978-1-4615-5325-0_60

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A mitogenic and hormonal signalling network regulate mammalian cell division commitment time.

L Jimenez de Asua·M Goin·M Ortiz·M B Gomez de Alzaga

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Abstract

A basic property of mammalian cells is to retain the mitogenically induced "commitment" to undergo DNA replication even in the absence of stimuli. Recent findings on PGF2 alpha and hormone-induced Swiss 3T3 cell multiplication, reveal that this crucial cell cycle event can be regulated by several signalling mechanisms.

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3T3 Cells Alprostadil Animals Cell Cycle Cell Division DNA Replication Demecolcine Dinoprost Insulin Kinetics Mammals Mice Signal Transduction Journal Article Research Support, Non-U.S. Gov't

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L Jimenez de Asua, M Goin, M Ortiz, M B Gomez de Alzaga. 1997. A mitogenic and hormonal signalling network regulate mammalian cell division commitment time.. https://doi.org/10.1007/978-1-4615-5325-0_60

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