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PubMed · 9568388

Patterning of the embryonic forebrain.

J L Rubenstein·P A Beachy
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Abstract

The vertebrate forebrain is derived from the anterior neural plate, where anteroposterior, dorsoventral and local patterning mechanisms specify regional identify. The recent identification of genetic regulators of these processes has opened the way to elucidating how the major forebrain regions (i.e. cerebral cortex, basal ganglia, thalamus, and hypothalamus) are formed, and how molecular lesions in these processes cause human birth defects.

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AnimalsFemaleHumansPregnancyProsencephalonSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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J L Rubenstein, P A Beachy. 1998. Patterning of the embryonic forebrain.. https://doi.org/10.1016/s0959-4388(98)80004-4

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