PubMed · 9582673
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M D Cooper, C M Kracher. 1998. Topical fluorides.. https://pubmed.ncbi.nlm.nih.gov/9582673/
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PURPOSE: The purpose of this in vitro study was to compare caries resistance of sound human enamel following argon laser (AL) irradiation, as well as, combinations of topical fluoride foams and AL irradiation. METHODS AND MATERIALS: Thirty extracted human teeth were sectioned into four buccal windows and assigned to one of the following treatment groups: (1) no treatment/control; (2) low fluence (11.5 J/cm2) AL irradiation for 10 seconds; (3) 1.23% APF foam for 4 minutes followed by low fluence AL irradiation; (4) 2.0% NaF foam for 4 minutes followed by low fluence AL irradiation. Caries-like lesions were created by submerging the teeth in ten Cate solution (pH 4.5). Following a 96-hour exposure period, 100 microns longitudinal sections were prepared for polarized light evaluation. Visilog 5.1.1. image analysis software was used to obtain quantitative lesion depths. The Scheffe F-test was used to compare the lesion depths for each of the four treatment groups. RESULTS: Lesion depths were: 16.1 +/- 6 microns for control; 13.7 +/- 4 microns for AL irradiation alone; 12.1 +/- 4.3 microns for 1.23% APF foam before AL irradiation; and 11.4 +/- 5.9 microns for 2.0% NaF foam before AL irradiation. Significant difference (p < 0.05) was found between the control group and the 2.0% NaF foam before AL irradiation group. AL irradiation alone reduced lesion depth by 15% compared with the control lesion. When AL irradiation was combined with 1.23% APF foam treatment, lesion depth decreased by 25% compared with control lesions, and by 29% when combined with 2.0% NaF foam. CONCLUSION: Combining AL irradiation and 2.0% NaF foam treatment significantly enhances the resistance of sound enamel to an in vitro cariogenic challenge.
In this in vitro study, the fluoride ion release from three more-viscous conventional glass ionomer cements (GICs)--ChemFlex, Fuji IX GP, Ionofil Molar--four polyacid-modified resin composites (compomers)--Dyract AP, Compoglass F, Freedom, F2000--and a hybrid resin composite--Ariston pHc--were compared. The amounts of fluoride release from 3 x 2.7 mm specimens were measured over six weeks using a fluoride ion-selective electrode. After six weeks, the specimens were recharged with 2 ml of 1.23 per cent acidulated phosphate fluoride (APF) gel for four minutes. The recharged specimens were then assessed for the amounts of fluoride release over another six weeks. Statistical analyses were performed using one-way and repeated measures ANOVA. The GICs and Compoglass F showed significantly higher initial fluoride release rates during the first two days (p < 0.05). After the first two days, fluoride release rates from all materials dropped quickly and became essentially stabilized within three-five weeks, in an exponential mode. The recharging of the specimens with APF gel caused a brief, but significant, increase in fluoride release for all materials (p < 0.05), before decreasing to previous comparable rates. Compoglass F released relatively more fluoride, and Ariston pHc relatively less, after APF gel application than before. The lowest total amounts over the study were released by Dyract AP and Freedom. The newer compomers, as well as the newer more-viscous GICs, appear to act as fluoride reservoirs to varying extents.
OBJECTIVES: The aim of this research was to evaluate the effect of titanium tetrafluoride on dentine permeability in comparison with sodium fluoride and acidulated phosphate fluoride to determine their contribution to acid resistance of dentine. METHODS: Thirty-two dentine discs were prepared from extracted mandibular molars. The hydraulic conductance of all discs was measured before and after the formation of smear layer. The discs were then randomly divided into five experimental and one-control groups. Coronal surfaces of dentine discs were treated with either fluoride solutions of NaF, APF, 1% TiF4, 0.5% TiF4 and 0.1% TiF4 or de-ionised water. Following the measurement of hydraulic conductance, treated surfaces were subjected to 25% citric acid application. Then, final permeability measurements were made. The data were statistically analysed using ANOVA and Tukey's HSD multiple comparisons. RESULTS: While smear layer formation considerably reduced dentinal permeability of dentine discs, fluoride or de-ionised water application to smeared surfaces did not cause any significant change in hydraulic conductance (p > 0.05). After citric acid application, control and NaF groups showed higher permeability values than 1%, 0.5% and 0.1% TiF4 and APF groups (p < 0.01). CONCLUSION: Clinical use of acidic solutions of titanium tetrafluoride in dentine cavities may be considered since smeared dentine surfaces are modified to a stabile and acid-resistant state.