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PubMed · 9619099

Uncoupling growth from the cell cycle.

L A Johnston
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Abstract

How does a Drosophila wing grow to the appropriate size and shape? Although a collaboration of cell division with the patterning of cell fates seems obvious, almost nothing is known about how these two processes are coordinated during development. A recent paper finds that blocking cell division uncouples cell growth from the cell division cycle, displaying remarkable flexibility in the ability of the wing primordia to achieve the right proportions with fewer than normal cells.

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AnimalsCDC2 Protein KinaseCell CycleCell DivisionDNA ReplicationDrosophila melanogasterGene Expression RegulationInsect ProteinsMorphogenesisWings, AnimalJournal ArticleReview

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L A Johnston. 1998. Uncoupling growth from the cell cycle.. https://doi.org/10.1002/(sici)1521-1878(199804)20%3A4%3C283%3A%3Aaid-bies3%3E3.0.co%3B2-r

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