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PubMed · 963591

Data analysis of low-angle diffraction by.one-dimensional crystals.

M J Yeager
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CollagenCrystallographyFourier AnalysisMathematicsNeutronsPhotoreceptor CellsScattering, RadiationX-Ray DiffractionJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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M J Yeager. 1976. Data analysis of low-angle diffraction by.one-dimensional crystals.. https://pubmed.ncbi.nlm.nih.gov/963591/

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PubMed1995

Reduced thrombogenicity of type VI collagen as compared to type I collagen.

Type VI collagen has been recently identified as a major constituent of vascular subendothelium where it serves as a binding site for von Willebrand factor. The present study compares the functional characteristics of type VI collagen with those of type I collagen with respect to platelet aggregating and secretory activities. The differences between the two collagens in platelet aggregation and serotonin and beta-thromboglobulin release were found to be highly significant (p < 0.001, p < 0.0007, p < 0.005 respectively). Our results indicate that under in vitro conditions, type VI collagen stimulates a significantly lesser platelet activation and aggregation response than collagen I, suggesting that type VI collagen may play a role in vivo to limit the platelet thrombotic response following injury to the vascular subendothelium.

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