PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 9652485

Magnetoencephalography and magnetic source imaging.

T P Roberts·D Poeppel·H A Rowley
View original source ↗Export metadata ↓

Abstract

Current brain imaging techniques, such as computed tomography (CT) and magnetic resonance imaging (MRI), provide noninvasive, high-resolution images that depict fine anatomic structure and delineate pathology by control of image contrast and sensitivity to the physicochemical microenvironment. These methods, although invaluable for the identification, characterization, and localization of lesions, do not provide any assessment of the functional viability of brain tissues, nor of the spatial organization of sensory, motor, and cognitive systems. However, such additional functional information is of great significance to the clinician in the determination of treatment strategies and patient management.

Explore related subjects

Brain MappingChildDiagnostic Techniques, NeurologicalEpilepsyEvoked Potentials, SomatosensoryFemaleHumansImage EnhancementMagnetoencephalographyMalePerioperative CarePreoperative CareSensitivity and SpecificitySignal Processing, Computer-AssistedJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

T P Roberts, D Poeppel, H A Rowley. 1998. Magnetoencephalography and magnetic source imaging.. https://pubmed.ncbi.nlm.nih.gov/9652485/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2008

Corpus callosal connection mapping using cortical gray matter parcellation and DT-MRI.

Population maps of the corpus callosum (CC) and cortical lobe connections were generated by combining cortical gray matter parcellation with the diffusion tensor fiber tractography of individual subjects. This method is based on the fact that the cortical lobes of both hemispheres are interconnected by the corpus callosal fibers. T1-weighted structural MRIs and diffusion tensor MRIs (DT-MRI) of 22 right-handed, healthy subjects were used. Forty-seven cortical parcellations in the dorsal prefrontal cortex, ventral prefrontal cortex, sensory-motor cortex, parietal cortex, temporal cortex, and occipital cortex were semi-automatically derived from structural MRIs, registered to DT-MRI, and used to identify callosal fibers. The probabilistic connections to each cortex were mapped on entire mid-sagittal CC voxels that had anatomical homology between subjects as determined by spatial registration. According to the population maps of the callosal connections, the ventral prefrontal cortex and parts of the dorsal prefrontal cortex both project fibers through the genu and rostrum. The CC regions through which the superior frontal cortex passes extend into the posterior body. Fibers arising from the parietal lobe and occipital lobe run mainly through the splenium, while fibers arising from the sensory-motor cortex pass through the isthmus. In general, dorsal or medial cortical lobes project fibers through the dorsal region of the CC, while lateral cortical lobes project fibers through the ventral region of the CC. The probabilistic subdivision of the CC by connecting cortical gray matter provides a more precise understanding of the CC.

Brain Mapping↗
PubMed2007

Observer-independent analysis of high-resolution MR images of the human cerebral cortex: in vivo delineation of cortical areas.

Using high-resolution MRI, it is now possible to examine the living human cortex down to a resolution of less than 300 mum. Thus, in vivo imaging is now approaching the resolution that has been successfully used in histological analysis of the cerebral cortex for many years, e.g., low-magnification light microscopy. This allows unprecedented views of cortical microstructure that reflect defined histological features, specifically, individual cortical layers. As in histological brain mapping, it is possible to use the changes in the cortical lamination patterns to define individual cortical areas. This allows in vivo neuroanatomical maps to be generated for individual subjects and precise correlation of the results from functional imaging studies in these subjects with their own microanatomical information. To this end, we adapted the well-established observer-independent cytoarchitectonic mapping techniques for defining cortical borders based on changes in cortical lamination for in vivo parcellation of high-resolution structural MR images.

Brain Mapping↗
PubMed2007

Functional brain imaging: a window into the visuo-vestibular systems.

PURPOSE OF REVIEW: Advances have been made in identifying how areas involved in processing vestibular, ocular motor, and visual information are represented in the human cortex as well as the cortical interaction between these systems in healthy subjects. RECENT FINDINGS: While we know how some vestibular and ocular motor disorders modify visuo-vestibular interaction by changing the 'normal' cortical activation-deactivation patterns, it is still early days in functional magnetic resonance imaging studies of patients with specific disorders. Findings from current brain imaging studies of several vestibular, ocular motor, and cerebellar disorders are presented. SUMMARY: The promise of more insights into the complex neuronal networks of the human cortex is great.

Brain Mapping↗