Small-molecule-based strategies for controlling gene expression.

C Denison; T Kodadek

doi:10.1016/s1074-5521(98)90167-3

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PubMed · 9653545

Small-molecule-based strategies for controlling gene expression.

C Denison·T Kodadek

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Abstract

A central goal in chemical biology is to gain control over biological pathways using small molecules, and the mRNA-synthesizing machinery is a particular important target. New advances in our understanding of transcriptional regulation suggests strategies to manipulate these pathways using small molecules.

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Animals Drug Design Gene Expression Regulation Genetic Engineering Humans Models, Genetic Models, Molecular RNA, Messenger Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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C Denison, T Kodadek. 1998. Small-molecule-based strategies for controlling gene expression.. https://doi.org/10.1016/s1074-5521(98)90167-3

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