From selectors to realizators.

J Pradel; R A White

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PubMed · 9654026

From selectors to realizators.

J Pradel·R A White

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Abstract

In 1975 Antonio Garcia-Bellido proposed a framework for understanding the morphogenetic function of homeotic genes in terms of selector genes and realizator genes. Since then, much has been learnt of the molecular nature and expression patterns of the Hox selector genes. Our identification of realizator genes, and our understanding of how specific sets of realizators are activated in different segments, is still far from complete, however. Here we discuss the nature of the Hox target genes identified so far and the basis of the target specificity of Hox gene products.

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Animals DNA-Binding Proteins Drosophila Proteins Gene Expression Regulation, Developmental Genes, Homeobox Genes, Insect Genes, Regulator Homeodomain Proteins Transcription Factors Journal Article Review

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J Pradel, R A White. 1998. From selectors to realizators.. https://pubmed.ncbi.nlm.nih.gov/9654026/

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