Uncoupling proteins: beyond brown adipose tissue.

H C Freake

doi:10.1111/j.1753-4887.1998.tb06136.x

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Uncoupling proteins: beyond brown adipose tissue.

H C Freake

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Abstract

Uncoupling protein, originally described in the inner mitochondrial membrane of brown adipose tissue, permits the oxidation of fuels without the generation of adenosine triphosphate (ATP). Closely related proteins have now been found in many other tissues and shown to be regulated by thyroid hormones and dietary factors. These uncoupling proteins may play a significant role in energy expenditure, with implications for the development of human obesity.

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Adipose Tissue, Brown Animals Carrier Proteins Diet Gene Expression Humans Ion Channels Membrane Proteins Mitochondrial Proteins Obesity RNA, Messenger Thyroid Hormones Tissue Distribution Uncoupling Protein 1 Journal Article Review

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H C Freake. 1998. Uncoupling proteins: beyond brown adipose tissue.. https://doi.org/10.1111/j.1753-4887.1998.tb06136.x

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