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PubMed · 9667842

New technologies for high-throughput screening.

J J Burbaum·N H Sigal
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Abstract

To screen efficiently the millions of compounds that are synthesized using combinatorial and automated methods, dramatically improved assay technologies are currently needed. In 96-well microtiter plates, nonradioactive techniques (primarily fluorimetric) and cell-based functional methods have moved to the cutting edge, while clever assays that extract information from large bead-based combinatorial libraries have begun to show considerable promise. In the future, miniaturized assays that break out of the 96-well format will be enabled by innovative technologies for high-throughput screening.

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Chemistry, OrganicMiniaturizationSpectrometry, FluorescenceJournal ArticleReview

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BibTeXRIS

J J Burbaum, N H Sigal. 1997. New technologies for high-throughput screening.. https://doi.org/10.1016/s1367-5931(97)80111-1

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