Mefloquine and malaria prophylaxis.

doi:10.1136/dtb.1998.36320

PubMed · 9684417

Mefloquine and malaria prophylaxis.

Abstract

In the UK, mefloquine (Lariam-Roche) has been marketed since 1990 for both malaria prophylaxis and for acute treatment of falciparum malaria. In 1991, we concluded that prophylaxis with mefloquine was appropriate for those travelling to areas where strains of Plasmodium falciparum resistant to chloroquine and proguanil are common. Since then, UK recommendations have changed several times. Recently, mefloquine's use as a prophylactic has been questioned because of reports of neuropsychiatric unwanted effects. This article discusses the place of f2p4oquine in malaria prophylaxis in light of these concerns.

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Antimalarials Central Nervous System Diseases Drug Administration Schedule Humans Malaria, Falciparum Mefloquine Journal Article Review

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1998. Mefloquine and malaria prophylaxis.. https://doi.org/10.1136/dtb.1998.36320

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