Complement, cytokines, and adhesion molecule expression in inflammatory reactions.

B J Czermak; H P Friedl; P A Ward

PubMed · 9686678

Complement, cytokines, and adhesion molecule expression in inflammatory reactions.

Abstract

Directional emigration of neutrophils is the hallmark of phlogistic processes. The involved regulatory mechanisms include complement activation products, cytokines, adhesion molecules, and their respective counter receptors. In this article, we discuss the role of these mediators in initiation, development, and containment of acute inflammatory responses in in vitro and in vivo models, showing interactions between a network of proinflammatory and anti-inflammatory effectors. A major focus deals with the effects of complement on activation of the vascular endothelium. In addition, the role of interleukins in the regulation of inflammatory responses is described.

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Animals Cell Adhesion Molecules Complement System Proteins Cytokines Humans Inflammation Inflammation Mediators Journal Article Review

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B J Czermak, H P Friedl, P A Ward. Complement, cytokines, and adhesion molecule expression in inflammatory reactions.. https://pubmed.ncbi.nlm.nih.gov/9686678/

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