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PubMed · 9686777

Pallidotomy for generalized dystonia.

W G Ondo·J M Desaloms·J Jankovic·R G Grossman
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Abstract

We systematically evaluated the efficacy of both unilateral and bilateral stereotactic pallidotomy in eight patients with generalized dystonia. Six patients had a marked improvement in dystonic movements and motor function; the other two patients also benefited from the procedure but to a lesser extent. The severity of dystonia was assessed before and after surgery by the Burke-Marsden-Fahn Dystonia Scale (BMFDS), the Unified Dystonia Rating Scale (UDRS), and the Activity of Daily Living Scale (ADL). The BMFDS scores decreased by 59.0%, UDRS by 62.5%, and ADL by 47.8% postoperatively. Adverse events were limited to a transient weakness in one patient. We conclude that pallidotomy is a safe and effective treatment in medically refractory cases of generalized dystonia.

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Activities of Daily LivingAdolescentAdultBrain MappingChildDominance, CerebralDystoniaFemaleGlobus PallidusHumansMaleMiddle AgedMotor SkillsNeurologic ExaminationPostoperative ComplicationsStereotaxic TechniquesTreatment OutcomeCase ReportsJournal Article

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W G Ondo, J M Desaloms, J Jankovic, R G Grossman. 1998. Pallidotomy for generalized dystonia.. https://doi.org/10.1002/mds.870130415

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