PubMed · 9691074
Oligonucleotide libraries--variatio delectat.
Abstract
In vitro selection of combinatorial nucleic acid libraries leads to specific target-binding molecules--RNA, single stranded DNA, modified RNA or modified DNA, commonly designated as aptamers--and to novel catalytic nucleic acids. The current state of aptamer and ribozyme technology is such that it establishes itself as a means of obtaining useful tools for molecular biology, diagnostics, molecular medicine and bio-organic chemistry.
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M Famulok, A Jenne. 1998. Oligonucleotide libraries--variatio delectat.. https://doi.org/10.1016/s1367-5931(98)80004-5
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