Comparative methods for identifying functional domains in protein sequences.

S Henikoff

doi:10.1016/s1387-2656(08)70050-4

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Comparative methods for identifying functional domains in protein sequences.

S Henikoff

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Abstract

This chapter reviews the different approaches that have been applied to the problem of protein motif identification. Several methods are available for finding motifs within protein families, for clustering databases to identify family relationships and for searching databases that consist of motif representations. With the rapid expansion of sequence databases, which currently appear to represent most protein families, these methods are becoming increasingly important for interpretation of molecular sequence information.

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Amino Acid Sequence Animals Biotechnology Databases as Topic Humans Molecular Sequence Data Peptide Library Protein Folding Proteins Sequence Alignment Sequence Homology, Amino Acid Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.Review

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S Henikoff. 1995. Comparative methods for identifying functional domains in protein sequences.. https://doi.org/10.1016/s1387-2656(08)70050-4

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