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PubMed · 9710898

Enalapril microbial biosensor.

S Fleschin·C Bala·A A Bunaciu·A Panait·H Y Aboul-Enein
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Abstract

Enalapril maleate (EMa) belongs to a new class of antihypertensive agents known as angiotensin converting enzyme (ACE) inhibitors. This paper describes the development of a microbial biosensor for EMa using induced Bacillus subitilis cells. This biosensor measures the acceleration of respiration during specific metabolic pathways of this drug. It has been applied, with good results, for determination of the active ingredient in the pharmaceutical tablet formulations.

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Antihypertensive AgentsBacillus subtilisBiosensing TechniquesCalibrationEnalaprilHydrogen-Ion ConcentrationOxygenOxygen ConsumptionPharmaceutical PreparationsTemperatureJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

S Fleschin, C Bala, A A Bunaciu, A Panait, H Y Aboul-Enein. 1998. Enalapril microbial biosensor.. https://doi.org/10.1080/10826069808010140

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