Xenopus eomesodermin is expressed in neural differentiation.

K Ryan; K Butler; E Bellefroid; J B Gurdon

doi:10.1016/s0925-4773(98)00084-7

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Xenopus eomesodermin is expressed in neural differentiation.

K Ryan·K Butler·E Bellefroid·J B Gurdon

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Abstract

Our initial description of the Xenopus gene Eomesodermin (Eomes) indicated that it is expressed largely if not entirely in mesodermal cells of gastrula stage embryos. A more detailed examination, described here, shows that it continues to be expressed in the most anterior (future head) mesoderm during gastrula and neurula stages. However, during tail-bud stages, Eomes expression is re-born in the most anterior part of the brain, becoming strongly transcribed in the olfactory region of the telencephalon. This later Eomes expression marks a very localized region of the forebrain distinct from that of Otx-2, anterior to that of En-1 and overlapping that of Sox-3.

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Animals Cell Differentiation DNA-Binding Proteins Embryo, Nonmammalian Embryonic Development Gene Expression Regulation, Developmental High Mobility Group Proteins Homeodomain Proteins In Situ Hybridization Nerve Tissue Proteins Nervous System Otx Transcription Factors SOXB1 Transcription Factors T-Box Domain Proteins Trans-Activators Transcription Factors Xenopus Xenopus Proteins Journal Article

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K Ryan, K Butler, E Bellefroid, J B Gurdon. 1998. Xenopus eomesodermin is expressed in neural differentiation.. https://doi.org/10.1016/s0925-4773(98)00084-7

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