The eosinophil ribonucleases.

H F Rosenberg

doi:10.1007/s000180050208

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The eosinophil ribonucleases.

H F Rosenberg

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Abstract

The eosinophil ribonucleases, eosinophilderived neurotoxin (EDN/RNase 2) and eosinophil cationic protein (ECP/RNase 3) are two closely related proteins with intriguing functional and evolutionary properties. While both EDN and ECP maintain the structural and catalytic residues typical of the RNase A superfamily, the role of ribonuclease activity in the physiologic function of these proteins remains unclear. The biochemistry and physiology of EDN, ECP and the recently discovered ribonuclease k6 (RNase 6) will be reviewed in this chapter.

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Amino Acid Sequence Animals Eosinophils History, 19th Century History, 20th Century Humans Molecular Sequence Data Phylogeny Ribonucleases Sequence Homology, Amino Acid Historical Article Journal Article Review

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H F Rosenberg. 1998. The eosinophil ribonucleases.. https://doi.org/10.1007/s000180050208

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