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Bone remodelling: a signalling system for osteoclast regulation.

E Filvaroff·R Derynck
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Abstract

Two physiological regulators of osteoclast maturation have recently been identified: the secreted protein osteoprotegerin and the cell-surface ligand to which it binds. These proteins are likely to play an important part in the control of bone resorption, but are also likely to have important roles in other tissues.

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AnimalsAntigens, CDApoptosis Regulatory ProteinsBone RemodelingCalcitriolCarrier ProteinsCell DifferentiationCyclic AMP-Dependent Protein KinasesCytokine Receptor gp130Gene Expression RegulationGlycoproteinsHumansMacrophage Colony-Stimulating FactorMembrane GlycoproteinsMiceMice, Mutant StrainsNF-kappa BOsteoblastsOsteoclastsOsteopetrosisOsteoprotegerinParathyroid HormoneRANK LigandReceptor Activator of Nuclear Factor-kappa BReceptors, Cytoplasmic and NuclearReceptors, SteroidReceptors, Tumor Necrosis FactorSignal TransductionTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaJournal ArticleReview

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E Filvaroff, R Derynck. 1998-09-24. Bone remodelling: a signalling system for osteoclast regulation.. https://doi.org/10.1016/s0960-9822(98)70434-8

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