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PubMed · 9768354

Size control: cell proliferation does not equal growth.

T T Su·P H O'Farrell
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Abstract

Division subdivides mass without increasing it. So one should not expect that an increase in cell division would make an organism bigger. Both classic and recent experiments confirm this simple rationale: altering proliferation produces normally sized body structures with either especially small or exceptionally large cells.

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AnimalsCDC2 Protein KinaseCarrier ProteinsCell Cycle ProteinsCell DivisionCell SizeDNA-Binding ProteinsDrosophila ProteinsDrosophila melanogasterE2F Transcription FactorsEmbryo, NonmammalianGrowthInsect ProteinsPhosphoprotein PhosphatasesPupaRetinoblastoma-Binding Protein 1Trans-ActivatorsTranscription FactorsWings, Animalcdc25 PhosphatasesJournal ArticleReview

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T T Su, P H O'Farrell. 1998-09-24. Size control: cell proliferation does not equal growth.. https://doi.org/10.1016/s0960-9822(98)70436-1

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