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Synergistic approaches based on nonchromatographic continuous separation techniques (solid-phase extraction and pervaporation) and chromatography couplings.

M D Luque de Castro·J M Fernández-Romero
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Abstract

Approaches based on continuous separation units coupled to either liquid or gas chromatography for improving the features of analytical methods are proposed. Examples of solid-phase separation-liquid chromatography for the determination of fat-soluble vitamins and their metabolites in clinical samples, and pervaporation-gas chromatography for the determination of volatile compounds in solid environmental samples are described. The clean-up and preconcentration effect achieved by the former coupling and the easy and effective solid-sample pretreatment in the latter clearly show their utility. The use of pervaporation as an advantageous alternative to headspace is demonstrated.

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CholecalciferolChromatography, GasChromatography, LiquidHumansJournal ArticleResearch Support, Non-U.S. Gov'tReview

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M D Luque de Castro, J M Fernández-Romero. 1998-09-11. Synergistic approaches based on nonchromatographic continuous separation techniques (solid-phase extraction and pervaporation) and chromatography couplings.. https://doi.org/10.1016/s0021-9673(98)00431-2

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